Table 1. Serum parameters of bone formation biomarkers (serum concentrations of osteocalcin and alkaline phosphatase, evidences of osteoblastic function) and a urinary Deoxypyridinolines/creatinine excretion fraction, (biomarker for collagen degradation and, therefore, osteclastic activation). I addition, Table 1 shows other mineral metabolism elements measurements, particularly, concentrations of plasma and urinary of calcium (Ca²⁺), magnesium (Mg²⁺), urea, and phosphurus (Pi). Renal function was also showed in this table coorbrating previous data from our group [8] such as albuminuria, microalbunuira, and creatinine clearance (calculated by the formula: Ccrea=mass of urinary of creatinine excreted during 24h/plasma creatinine, expressed in dL/h) demonstrating that renal failure is taking place in TBT animals as described before by our group [8, 10]. * Statically significant, p < 0.05